A Palestinian rammed a group of Israelis with a car at a junction in the West Bank on Sunday, wounding three of them, and was then killed by security forces, police said.
The alleged attacker was said to have driven the car into an area south of Nablus where Israelis typically gather to hitch rides. A checkpoint is located nearby and Israeli border police opened fire.
Israeli public radio described two of the wounded as in a serious condition.
The incident was the latest in a wave of knife, gun and car attacks to hit Israel and the Palestinian territories since the start of October.
The violence has left 73 Palestinians dead, around half of them alleged attackers. Nine Israelis have also been killed as well as one Arab Israeli.
Violent protests have also erupted in east Jerusalem, the occupied West Bank and the Gaza Strip.
Unrest has waned somewhat in recent days, though sporadic attacks have continued.